Reading Diary 6
Reading Diary 6
5 null terms
- convalescent
- A person who is getting well again after an illness or a medical operation.
- Example: Notably, mutations emerging under selective pressure from convalescent plasma may be different from those selected by the most frequent mAb isolated from the same plasma.
W. T. Harvey et al., “SARS-CoV-2 variants, spike mutations and immune escape,” Nature Reviews Microbiology, vol. 19, no. 7, pp. 409–424, Jun. 2021, doi: 10.1038/s41579-021-00573-0.
- en: выздоравливающий
- deleterious
- Harmful and damaging.
- Example: As highly deleterious mutations are rapidly purged, most mutations observed in genomes sampled from circulating SARS-CoV-2 virions are expected to be either neutral or mildly deleterious.
W. T. Harvey et al., “SARS-CoV-2 variants, spike mutations and immune escape,” Nature Reviews Microbiology, vol. 19, no. 7, pp. 409–424, Jun. 2021, doi: 10.1038/s41579-021-00573-0.
- en: вредный, вредоносный, пагубный, опасный
- mink
- A small wild animal with thick shiny fur, a long body and short legs. Mink are often kept on farms for their fur.
- Example: Another RBM amino acid change, Y453F — associated with increased ACE2-binding affinity19 — received considerable attention following its identification in sequences associated with infections in humans and mink; most notably one lineage identified in Denmark and initially named ‘cluster 5’ .
W. T. Harvey et al., “SARS-CoV-2 variants, spike mutations and immune escape,” Nature Reviews Microbiology, vol. 19, no. 7, pp. 409–424, Jun. 2021, doi: 10.1038/s41579-021-00573-0.
- en: норка
- to dislodge
- To force or knock something out of its position.
- Example: Mutations at those sites (for example, C136Y and S12P, which alter the cleavage occurring between residues C15 and V16) have been shown to affect the neutralizing activity of several mAbs, likely disrupting the disulfide bond and therefore dislodging the supersite targeted by several antibodies.
W. T. Harvey et al., “SARS-CoV-2 variants, spike mutations and immune escape,” Nature Reviews Microbiology, vol. 19, no. 7, pp. 409–424, Jun. 2021, doi: 10.1038/s41579-021-00573-0.
- en: вытеснять, смещать
- to purge
- To get rid of something.
- Example: As highly deleterious mutations are rapidly purged, most mutations observed in genomes sampled from circulating SARS-CoV-2 virions are expected to be either neutral or mildly deleterious.
W. T. Harvey et al., “SARS-CoV-2 variants, spike mutations and immune escape,” Nature Reviews Microbiology, vol. 19, no. 7, pp. 409–424, Jun. 2021, doi: 10.1038/s41579-021-00573-0.
- en: удалять, очищать, вычищать